Significance of Malignant Peritoneal Cytology on the Survival of Women with Early-Stage Cervical Cancer: A Japanese Gynecologic Oncology Group Study.

Significance of Malignant Peritoneal Cytology on the Survival of Women with Early-Stage Cervical Cancer: A Japanese Gynecologic Oncology Group Study.

This examine examined the affiliation between peritoneal cytology and survival in early-stage cervical most cancers. This is a nationwide multicenter retrospective examine, analyzing consecutive girls with scientific stage IB1-IIB cervical most cancers who underwent radical hysterectomy with obtainable peritoneal cytology outcomes from 2004-2008.

Propensity rating inverse likelihood of therapy weighting was used to evaluate the influence of malignant peritoneal cytology on survival. Among 1409 analyzed circumstances, 88 (6.2%) had malignant peritoneal cytology. On weighted fashions, malignant peritoneal cytology was related with decreased disease-free survival (hazard ratio (HR) 1.78, 95% confidence interval (CI) 1.36-2.32) and total survival (OS, HR 1.93, 95% CI 1.44-2.59).

On sensitivity analyses, malignant peritoneal cytology was related with decreased OS in adenocarcinoma/adenosquamous carcinoma, high-risk early-stage illness and those that acquired concurrent chemo-radiotherapy. However, amongst girls who acquired postoperative systemic chemotherapy, malignant peritoneal cytology was not related with OS (HR 1.21, 95% CI 0.72-2.04).

A systematic evaluation, together with our outcomes, confirmed that malignant peritoneal cytology was related with decreased OS (HR 4.03, 95% CI 1.81-8.99) and elevated recurrence in squamous carcinoma (odds ratio 1.89, 95% CI 1.05-3.39) and adenocarcinoma (odds ratio 4.30, 95% CI 2.30-8.02). In conclusion, the presence of malignant cells in peritoneal cytology is related with decreased survival in early-stage cervical most cancers. The doable profit of systemic chemotherapy on this subgroup deserves additional investigation.

Although the charges are usually low (0.2%-10%), unsatisfactory Papanicolaou (Pap) checks are related with an elevated danger of epithelial lesions on subsequent follow-up. Therefore, some research have advisable further laboratory processing, resampling of sufferers, and extra not too long ago, human papillomavirus testing.Consecutive circumstances signed out as unsatisfactory for analysis (UE) have been recognized from January 1, 2008 to December 31, 2010 in the cytology laboratory at Houston Methodist Hospital.

Patient’s demographics, related prior scientific historical past, kind of Pap check, causes for UE prognosis, and cytology or histology follow-up have been obtained from the pathology database.Among 56,563 complete Pap checks, 276 have been signed out as UE (0.47%). Nearly half of these sufferers have been older than 50 years (15 to 88 years). The majority (85%) of sufferers over 50 years outdated had a historical past of prior gynecologic most cancers. Low squamous cellularity was the commonest trigger of UE in all age teams.

Follow-up abnormalities have been recognized in 21 of 73 sufferers (29%).Low squamous cellularity was the commonest trigger of UE and was typically seen in girls older than 50 years of age.The common rating for the first check set was considerably greater for residents who acquired formal coaching by a cytotechnologist than for many who didn’t. Overall, 16 of 90 slides have been misclassified by 40% or extra of residents, half of which exhibited glandular abnormalities.The goal evaluation offered by mock PT is a great tool for each college and residents.

Mock gynecologic cytology proficiency testing as a milestone evaluation device for anatomic pathology residents.

One of the main goals of the Next Accreditation System is to maneuver towards an outcomes-based analysis system the place every accredited medical residency program should exhibit that its residents are competent in performing the important duties needed for scientific follow. The vital danger related with UE emphasizes the significance of acceptable follow-up on these sufferers.

Because all pathologists who sign-out or display screen Papanicolaou (Pap) checks are required to move an annual 10-slide gynecologic cytology proficiency check (PT), we developed mock PT modules as a device for assessing competency.In 2007, we launched mock proficiency testing with Three distinct modules, every consisting of 3 10-slide check units (10 ThinPrep, 10 SurePath, and 10 standard Pap slides).

Each module was administered at Three completely different time factors. We evaluated the following parameters: (1) efficiency variations between Pap preparations; (2) efficiency over time; (3) efficiency earlier than and after initiation of one-on-one instructing periods with cytotechnologists in 2009; and (4) high quality of check slides.Residents confirmed enchancment over time, and total scores didn’t differ considerably amongst ThinPrep, SurePath, and traditional slide units.

Significance of Malignant Peritoneal Cytology on the Survival of Women with Early-Stage Cervical Cancer: A Japanese Gynecologic Oncology Group Study.

Pancreatobiliary duct brushing cytopathology: an evaluation of the CAP Non-Gynecologic Cytology (NGC) program for pancreatic pathology 2000-2011.

<AbstractText>The College of American Pathologists (CAP, Northfield, Illinois) displays efficiency in cytologic evaluation to guage the commonplace of follow and take into account methods for methodology enchancment.</AbstractText><AbstractText>5700 responses to 97 pancreatobiliary tract brushing slide challenges have been collected by the CAP Non-Gynecologic Cytopathology (NGC) Program, between 2000 and 2011.

Analysis examined participant settlement with the common diagnostic classes of benign or malignant. Suspicious responses have been categorised as concordant with slides having a optimistic common prognosis. Conventional smears with Pap stain and Romanowsky stain have been evaluated along with CytoSpin, ThinPrep, and SurePath preparations. ThinPrep, or SurePath.</AbstractText><AbstractText>Participants carried out properly with better than 90% settlement with the goal diagnostic class.

A nonlinear combined mannequin was match with Three factors-general prognosis, participant kind, and preparation kind.</AbstractText><AbstractText>Overall concordance price was 91.7%. Preparation kind and common prognosis have been considerably related with the concordance price. The interplay time period between these two elements was additionally statistically vital, with ThinPrep performing marginally higher for optimistic circumstances and CytoSpin performing higher for detrimental circumstances. Conventional smears didn’t carry out in addition to CytoSpin,

Wright Stain

21770034-1 25 g
EUR 46.61

Wright Stain

21770034-2 100 g
EUR 165.71

Wright Stain

13111 25 Gms
EUR 4.5
Description: Part B

Wright stain, certified

02785-100 100g
EUR 274
Description: 68988-92-1

Wright stain, certified

02785-25 25g
EUR 95
Description: 68988-92-1

Wright-Giemsa Solution

WGS3800 1 Gal.
EUR 102.85

Wright-Giemsa Solution

WGS500 500 ml
EUR 28.28

Wright-Giemsa Solution

WGS999 1000 ml
EUR 45

Wright Staining Solution

K1182-100 100ml
EUR 40
Description: Cell Biology|Staining Solution

Wright Staining Solution

K1182-500 500ml
EUR 64
Description: Cell Biology|Staining Solution

Wright-Giemsa Solution

M1438-1000 each
EUR 379.2

Wright-Giemsa Solution

M1438-500 each
EUR 248.4

DNA-Sorb-D DNA extraction kit from liquid-based cytology samples (Cytoscreen,

K-1-8-100 100
EUR 245.25

Wright-Giemsa Stain Kit

WGK-1 1 kit(s)
EUR 52.72

Wright-Giemsa Stain Kit

WGK-2 1 kit(s)
EUR 27

Wright-Giemsa Stain Kit

K1438-30 each
EUR 314.4

Wright-Giemsa Stain Kit

K1438-500 each
EUR 444

StainRITE® Wright Stain Solution

24986-1 1L
EUR 89

StainRITE® Wright Stain Solution

24986-20 20L
EUR 356

StainRITE® Wright Stain Solution

24986-4 4L
EUR 190

Synthetic Broth, AOAC (Wright and Mundy

M334-500G 1 unit
EUR 45.2
Description: Synthetic Broth, AOAC (Wright and Mundy

StainRITE® Wright-Giemsa Stain Solution

24985-1 1L
EUR 128

StainRITE® Wright-Giemsa Stain Solution

24985-10 10L
EUR 506

StainRITE® Wright Stain Phosphate Buffer pH 6.8

24989-1 1L
EUR 60

StainRITE® Wright-Giemsa Stain Phosphate Buffer pH 6.8

24984-1 1L
EUR 56

StainRITE® Wright-Giemsa Stain Phosphate Buffer pH 6.8

24984-4 4L
EUR 144

Fixative, for fixing cytological or hist

S102-500ML 1 unit
EUR 31.73
Description: Fixative, for fixing cytological or hist

Wright's stain

GT7819 10g
EUR 144.84

Wright's stain

GT7819-10 10
EUR 15.9

Wright's stain

GT7819-100 100
EUR 79.1

Wright's stain

GT7819-100G 100 g
EUR 132

Wright's stain

GT7819-10G 10 g
EUR 55.2

Wright's stain

GT7819-25 25
EUR 27.8

Wright's stain

GT7819-250 250
EUR 158.2

Wright's stain

GT7819-250G 250 g
EUR 228

Wright's stain

GT7819-25G 25 g
EUR 69.6

Wrights Stain

S030-500ML 1 unit
EUR 8.52
Description: Wrights Stain

Wright’s stain, Hi-CERT™

GRM265-25G 1 unit
EUR 25.94
Description: Wright’s stain, Hi-CERT™

Wright’s stain, Hi-CERT™

GRM265-5G 1 unit
EUR 6.93
Description: Wright’s stain, Hi-CERT™

Wrightiadione

TBZ1039 unit Ask for price

Wrights - Giemsa Stain

RRSP978-D 500ml
EUR 10.19

Wrights - Giemsa Stain

RRSP978-E 1L
EUR 14.76

Wrights - Giemsa Stain

RRSP978-F 2.5L
EUR 22.73

Wright’s Stain, Certified

S030-250ML 1 unit
EUR 4.88
Description: Wright’s Stain, Certified

Wrights Stain (Modified)

RRSP153-D 500ml
EUR 9.25

Wrights Stain (Modified)

RRSP153-E 1L
EUR 12.49

Wrights Stain (Modified)

RRSP153-F 2.5L
EUR 19.31

Wright's stain (Eosin methyl blue)

WB0989 25g
EUR 91.32

Wright's Stain Buffer Solution

37216-34 100ML
EUR 14

Wrights Blood Stain certified

W00180 25G
EUR 154.23

boite de 200 filtres pour cytologie, 24 x 76 mm + 1 trou 7 mm

CY430F2476/1T 200
EUR 13.1

boite de 200 filtres pour cytologie, 26 x 63 mm + 1 trou

CY430F2663/1T 200
EUR 13.1

boite de 200 filtres pour cytologie, 25 x 75 mm + 2 trous

CY430F2575/2T 200
EUR 13.1

Cytological Sampling Brush - PK100

CYT1050 PK100
EUR 63.45

Recombinant Dalea wrightii Maturase K (matK), partial

MBS1343675-INQUIRE INQUIRE Ask for price

Recombinant Ipomoea wrightii ATP synthase subunit beta, chloroplastic (atpB)

MBS1363455-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1355

Recombinant Ipomoea wrightii ATP synthase subunit beta, chloroplastic (atpB)

MBS1363455-002mgEColi 0.02mg(E-Coli)
EUR 1055

Recombinant Ipomoea wrightii ATP synthase subunit beta, chloroplastic (atpB)

MBS1363455-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Ipomoea wrightii ATP synthase subunit beta, chloroplastic (atpB)

MBS1363455-01mgEColi 0.1mg(E-Coli)
EUR 1230

Recombinant Ipomoea wrightii ATP synthase subunit beta, chloroplastic (atpB)

MBS1363455-01mgYeast 0.1mg(Yeast)
EUR 1310

Recombinant Cuphea wrightii 3-oxoacyl-[acyl-carrier-protein] synthase 3 B, chloroplastic (KAS3B)

MBS1123244-INQUIRE INQUIRE Ask for price

Recombinant Cuphea wrightii 3-oxoacyl-[acyl-carrier-protein] synthase 3 A, chloroplastic (KAS3A), partial

MBS1004055-INQUIRE INQUIRE Ask for price

Clip for Cyto Chamber - PK4

GBA1524 PK4
EUR 876.87

Mouse antibody for Cytomegalovirus

887 100 ug
EUR 431.93
Description: This is Mouse monoclonal FITC conjugated antibody against Cytomegalovirus pp65 for WB, ELISA.

ELISA Kit for Cytoglobin (CYGB)

SEC426Hu 96Т
EUR 700

ELISA Kit for Cytoglobin (CYGB)

SEC426Ra 96Т
EUR 760

Mouse antibody for Cytomegalovirus gB

826 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Cytomegalovirus gB for WB, ELISA.

Mouse antibody for Cytomegalovirus gH

861 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Cytomegalovirus gH for WB, ELISA.

ELISA Kit for Cytokeratin 9 (CK9)

SEA549Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 7 (CK7)

SEA556Hu 96Т
EUR 630

ELISA Kit for Cytochrome C (CYCS)

SEA594Hu 96Т
EUR 665

ELISA Kit for Cytochrome C (CYCS)

SEA594Mi 96Т
EUR 648

ELISA Kit for Cytochrome C (CYCS)

SEA594Mu 96Т
EUR 684

ELISA Kit for Cytochrome C (CYCS)

SEA594Po 96Т
EUR 756

ELISA Kit for Cytochrome C (CYCS)

SEA594Ra 96Т
EUR 722

ELISA Kit for Cytokeratin 5 (CK5)

SEA488Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 4 (CK4)

SEA489Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 1 (CK1)

SEA492Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 1 (CK1)

SEA492Ra 96Т
EUR 684

ELISA Kit for Cytokeratin 8 (CK8)

SEC025Hu 96Т
EUR 700

Mouse antibody for Cytomegalovirus pp65

885 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Cytomegalovirus pp65 for WB, ELISA.

ELISA Kit for Cytokeratin 14 (CK14)

SEA522Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 12 (CK12)

SEA535Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 16 (CK16)

SEA516Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 15 (CK15)

SEA517Hu 96Т
EUR 630

ELISA Kit for Cytokeratin 18 (CK18)

SEB231Hu 96Т
EUR 665

ELISA Kit for Cytokeratin 18 (CK18)

SEB231Mu 96Т
EUR 684

ELISA Kit for Cytokeratin 18 (CK18)

SEB231Po 96Т
EUR 798

ELISA Kit for Cytokeratin 18 (CK18)

SEB231Ra 96Т
EUR 722

ELISA Kit for Cytokeratin 19 (CK19)

SEB239Hu 96Т
EUR 665

ELISA Kit for Cytokeratin 19 (CK19)

SEB239Mu 96Т
EUR 684

ELISA Kit for Cytokeratin 10 (CK10)

SEB691Hu 96Т
EUR 665

ELISA Kit for Cytokeratin 17 (CK17)

SEB822Hu 96Т
EUR 665

ELISA Kit for Cytokeratin 13 (CK13)

SEB875Hu 96Т
EUR 665

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000695-10x96StripWells 10x96-Strip-Wells
EUR 6070

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000695-24StripWells 24-Strip-Wells
EUR 345

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000695-48StripWells 48-Strip-Wells
EUR 630

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000695-5x96StripWells 5x96-Strip-Wells
EUR 3380

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000695-96StripWells 96-Strip-Wells
EUR 850

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000798-10x96StripWells 10x96-Strip-Wells
EUR 6230

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000798-24StripWells 24-Strip-Wells
EUR 350

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000798-48StripWells 48-Strip-Wells
EUR 645

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000798-5x96StripWells 5x96-Strip-Wells
EUR 3465

CLIA Kit for Interaction Protein For Cytohesin Exchange Factors 1 (IPCEF1)

MBS2000798-96StripWells 96-Strip-Wells
EUR 870

Goat polyclonal antibody for Cytomegalovirus

7654 1 ml
EUR 373.2
Description: This is HRP conjugated goat polyclonal antibody against Cytomegalovirus AD 169 for WB, ELISA.

Goat polyclonal antibody for Cytomegalovirus

803 1 ml
EUR 347.1
Description: This is FITC conjugated goat polyclonal antibody against Cytomegalovirus AD 169 for WB, ELISA.

ELISA kit for Mouse Cytokine

KTE71626-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Mouse Cytokine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Cytokine

KTE71626-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Mouse Cytokine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Cytokine

KTE71626-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Mouse Cytokine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Cytokine

KTE63051-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Human Cytokine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Cytokine

KTE63051-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Human Cytokine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Cytokine

KTE63051-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Human Cytokine in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA Kit for Cytokeratin 20 (CK 20)

SEB240Hu 96Т
EUR 665

Mouse antibody for Cytomegalovirus late ag.

881 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Cytomegalovirus late ag for WB, ELISA.

Cyto-Blue, Cytoplasmic counterstain for countersta

NB354 100 ml
EUR 355
Description: Cyto-Blue, Cytoplasmic counterstain for counterstaining nuclear IHC& ICC stains such as ER, PR, Ki-67 and all antibodies staining nuclear markers, 100 ml (Large volume)

Cyto-Blue, Cytoplasmic counterstain for countersta

NB310 10 ml
EUR 139
Description: Cyto-Blue, Cytoplasmic counterstain for counterstaining nuclear IHC & ICC stains such as ER, PR, Ki-67 and all antibodies staining nuclear markers, 10 ml (Small volume)

ELISA Kit for Cytochrome P450 1A2 (CYP1A2)

SED294Hu 96Т
EUR 700

ELISA Kit for Cytochrome P450 1A2 (CYP1A2)

SED294Ra 96Т
EUR 760

ELISA Kit for Cytochrome P450 1A1 (CYP1A1)

SED295Hu 96Т
EUR 700

ELISA Kit for Cytochrome P450 1A1 (CYP1A1)

SED295Ra 96Т
EUR 760

ELISA Kit for Cytochrome P450 1B1 (CYP1B1)

SED297Hu 96Т
EUR 700

ELISA Kit for Cytochrome P450 3A4 (CYP3A4)

SED299Hu 96Т
EUR 700

ELISA Kit for Cytochrome P450 3A4 (CYP3A4)

SED299Mu 96Т
EUR 720

ELISA Kit for Cytochrome P450 2D6 (CYP2D6)

SED302Hu 96Т
EUR 700

There was no vital distinction between cytotechnologists and pathologists. Small vital variations have been discovered between preparations sorts. The statistical variations between focus methods could also be attributable to dissimilarities in the amount of cells and high quality of cytomorphology, thus affecting the interpretations by taking part laboratories.</AbstractText>

Cervical cancer screening by molecular Pap-transformation of gynecologic cytology.

Cervical cancer screening by molecular Pap-transformation of gynecologic cytology.
Cervical cancer is one of the widespread cancers in girls accounting for 7.9% of all cancers. In India it’s the second commonest cancer in girls. The immortality of the cancer cell and the comparatively lengthy timeframe from acquisition of an infection to growth of cervical cancer was established.
As main developments like LBC, HPV testing have been launched within the current years, screening has taken a brand new avatar, the Molecular pap!! The goals of this research have been: To evaluate gynecologic cytology and irregular outcomes with respect to standard and LBC. To research the function of HPV cotesting and ancillary checks carried out, that’s, HPV CISH, and p16ink4a by IHC.
About 71 924 Conventional and LBC samples have been included from August 2009 to December 2017. Cases for HPV testing alongside the traditional smears have been 1539. HPV could be examined from the identical LBC vial because the pattern stays steady at room temperature for six weeks. HPV DNA PCR was carried out in our laboratory for High and Low danger genotypes.
Cytology findings have been additionally correlated with histology. Detection charge of SILs in LBC samples have been greater (2.20%). The commonest abnormality was LSIL in LBC and ASCUS in typical smears. LBC with HPV cotesting improves sensitivity and specificity and reduces ambiguous outcomes; permits higher compliance, as a adverse outcome of each checks permits sufferers to get screening each 5 years, thereby rising screening intervals, essential in a useful resource restricted state of affairs.

Touch imprint (TI) cytology of needle core biopsies (NCB) in pathology laboratories: A observe survey of contributors within the College of American Pathologists (CAP) Non Gynecologic Cytopathology (NGC) Education Program.

Intra-procedural evaluation of contact imprint (TI) cytology from needle core biopsies (NCB) is used to make sure pattern adequacy and to offer rapid prognosis in numerous settings. We aimed to survey laboratories for present practices on the use of cytology with NCB. A voluntary supplemental questionnaire together with questions on demographics, personnel concerned, websites, accessioning, and reporting was despatched with the College of American Pathologists (CAP) 2015 Non gynecologic Cytopathology Education Program to survey practices of cytologic evaluation of NCB.
Among 844 respondents, 403 (48%) carried out cytologic evaluation of NCB. Common physique websites included lung (94%; 368/392), liver (87%; 340/ 392), and lymph nodes/spleen (77%; 303/392). Most of the time, a pathologist was current on-site 75% (295/393) for adequacy evaluation which was often verbally reported to the supplier performing the process.
Specimens have been ready by cytotechnologists (50%; 193 of 388) or pathologists (45%; 176 of 388) by touching the core to the slide (50%; 196 of 390) and rolling the core on the slide (45%; 177/390). Among the respondents, 19% stated that cytotechnologists independently carried out rapid evaluation of TI of NCB. Most laboratories (69%; 264/384) evaluated air-dried slides with a modified Giemsa stain and rendered one TI/NCB mixed report (87%, 334/385).
Cervical cancer screening by molecular Pap-transformation of gynecologic cytology.

p16/Ki-67 dual-stained cytology for detecting cervical (pre)cancer in a HPV-positive gynecologic outpatient inhabitants.

Women who check optimistic for a high-risk sort of the human papillomavirus (HPV) require triage testing to determine these girls with cervical intraepithelial neoplasia grade Three or cancer (≥CIN3). Although Pap cytology is taken into account a gorgeous triage check, its applicability is hampered by its subjective nature. This research prospectively in contrast the scientific efficiency of p16/Ki-67 dual-stained cytology to that of Pap cytology, with or with out HPV16/18 genotyping, in high-risk HPV-positive girls visiting gynecologic outpatient clinics (n=446 and age 18-66 years).

From all girls, cervical scrapes (for Pap cytology, HPV16/18 genotyping, and p16/Ki-67 dual-stained cytology) and colposcopy-directed biopsies have been obtained. This is the primary survey carried out particularly to find out the observe of adequacy evaluation of TI of NCB. Cytotechnologists are usually not performing adequacy evaluation of TI with out pathologist oversight. A single report is often issued which incorporates the adequacy evaluation as a component of the ultimate report.

The sensitivity of p16/Ki-67 dual-stained cytology for ≥CIN3 (93.8%) did neither differ considerably from that of Pap cytology (87.7%; ratio 1.07 and 95% confidence interval (CI): 0.97-1.18) nor from that of Pap cytology mixed with HPV16/18 genotyping (95.1%; ratio 0.99 and 95% CI: 0.91-1.07). However, the specificity of p16/Ki-67 dual-stained cytology for ≥CIN3 (51.2%) was considerably greater than that of Pap cytology (44.9%; ratio 1.14 and 95% CI: 1.01-1.29) and Pap cytology mixed with HPV16/18 genotyping (25.8%; ratio 1.99 and 95% CI: 1.68-2.35).

After exclusion of girls who had been referred as a result of of irregular Pap cytology, the specificity of p16/Ki-67 dual-stained cytology for ≥CIN3 (56.7%) remained the identical, whereas that of Pap cytology (60.3%) elevated considerably, leading to the same specificity of each assays (ratio 0.94 and 95% CI: 0.83-1.07) on this sub-cohort. In abstract, p16/Ki-67 dual-stained cytology has a superb scientific efficiency and is an fascinating goal microscopy-based triage device for high-risk HPV-positive girls.

Gill’s Hematoxylin #2, double strength for Histology & Cytology

24243-1000 1000ml
EUR 108
Description: 7732-18-5

Gill’s Hematoxylin #2, double strength for Histology & Cytology

24243-500 500ml
EUR 65
Description: 7732-18-5

Blood Brain Barrier Transportation Media

TMBBB001 500ml bottle
EUR 0.1

VIRAL TRANSPORT MEDIUM

7574001 1ML
EUR 132.98

Viral Transport Medium

IGVTM1000ML each
EUR 317
Description: Viral Transport Medium

Viral Transport Medium

IGVTM500ML each
EUR 168
Description: Viral Transport Medium

Transport Medium (Stuart)

M306-100G 1 unit
EUR 18.4
Description: Transport Medium (Stuart)

Transport Medium (Stuart)

M306-500G 1 unit
EUR 66.24
Description: Transport Medium (Stuart)

VIRAL TRANSPORT MEDIUM, 1LTR

7574001-1LTR 1LTR
EUR 250.11

Transport Liquid Medium

M1487-500G 1 unit
EUR 45.2
Description: Transport Liquid Medium

Bile Peptone Transport Medium

M481-500G 1 unit
EUR 45.39
Description: Bile Peptone Transport Medium

VIRAL TRANSPORT MEDIUM, 1 ML

7574001-A 1ML
EUR 30.49

Transport Charcoal Medium

M315-500G 1 unit
EUR 47.68
Description: Transport Charcoal Medium

Michel™s Transport Medium

24353-500 500ml
EUR 171
Description: 7732-18-5

Transport Medium w/o Charcoal

M202-100G 1 unit
EUR 17.21
Description: Transport Medium w/o Charcoal

Transport Medium w/o Charcoal

M202-500G 1 unit
EUR 47.87
Description: Transport Medium w/o Charcoal

Amies Transport Medium w/ Charcoal

M651-100G 1 unit
EUR 15.93
Description: Amies Transport Medium w/ Charcoal

Amies Transport Medium w/ Charcoal

M651-500G 1 unit
EUR 39.31
Description: Amies Transport Medium w/ Charcoal

Viral Transport Medium Liquid Amies

IGVTMA1000ML each
EUR 145
Description: Viral Transport Medium Liquid Amies

Viral Transport Medium Liquid Amies

IGVTMA500ML each
EUR 81
Description: Viral Transport Medium Liquid Amies

VEAL INFUSION VIRAL TRANSPORT MEDIUM

7574002 1ML
EUR 59.77

Viral Transport Medium Veal Infusion

IGVTMV1000ML each
EUR 141
Description: Viral Transport Medium Veal Infusion

Viral Transport Medium Veal Infusion

IGVTMV500ML each
EUR 81
Description: Viral Transport Medium Veal Infusion

HiFungal™ Transport Medium w/swab

MS5478-25NO 1 unit
EUR 103.29
Description: HiFungal™ Transport Medium w/swab

HiFungal™ Transport Medium w/swab

MS5478-50NO 1 unit
EUR 184.3
Description: HiFungal™ Transport Medium w/swab

Stuart Transport Medium w/o Sodium

M1203-100G 1 unit
EUR 14.77
Description: Stuart Transport Medium w/o Sodium

Stuart Transport Medium w/o Sodium

M1203-500G 1 unit
EUR 42.63
Description: Stuart Transport Medium w/o Sodium

Transport Medium, Amies w/o Charcoal

M684-100G 1 unit
EUR 14.77
Description: Transport Medium, Amies w/o Charcoal

Transport Medium, Amies w/o Charcoal

M684-500G 1 unit
EUR 39.31
Description: Transport Medium, Amies w/o Charcoal

Stuart Transport Medium w/o Methylene

M1131-100G 1 unit
EUR 18.4
Description: Stuart Transport Medium w/o Methylene

Stuart Transport Medium w/o Methylene

M1131-500G 1 unit
EUR 66.24
Description: Stuart Transport Medium w/o Methylene

VEAL INFUSION VIRAL TRANSPORT MEDIUM, 1LTR

7574002-1LTR 1LTR
EUR 111.02

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

20-abx147914
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

20-abx015115
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • 5 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx027854-400ul 400 ul
EUR 627.6

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx027854-80l 80 µl
EUR 343.2

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

20-abx327220
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx330898-100ul 100 ul
EUR 510

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

20-abx311414
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx015115-100g 100 µg
EUR 43.75

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx027854-400l 400 µl
EUR 518.75

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx147914-1096tests 10 × 96 tests Ask for price

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx147914-596tests 5 × 96 tests
EUR 387.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx147914-96tests 96 tests
EUR 300

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx327220-100g 100 µg
EUR 250

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) Antibody

abx327220-50g 50 µg
EUR 187.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx375911-96tests 96 tests
EUR 337.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx311414-100g 100 µg
EUR 362.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx311414-20g 20 µg
EUR 162.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody

abx311414-50g 50 µg
EUR 250

VEAL INFUSION VIRAL TRANSPORT MEDIUM, 1 ML

7574002-A 1ML
EUR 14.39

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (HRP)

20-abx311415
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (FITC)

20-abx311416
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (HRP)

abx311415-100g 100 µg
EUR 362.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (HRP)

abx311415-20g 20 µg
EUR 162.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (HRP)

abx311415-50g 50 µg
EUR 250

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (FITC)

abx311416-100g 100 µg
EUR 362.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (FITC)

abx311416-20g 20 µg
EUR 162.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (FITC)

abx311416-50g 50 µg
EUR 250

Universal Transport Medium Collection Kit - PK50

346C PK50
EUR 392.85

Rat Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 2 (CNNM2) ELISA Kit

abx507610-96tests 96 tests
EUR 687.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (Biotin)

20-abx311417
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (Biotin)

abx311417-100g 100 µg
EUR 362.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (Biotin)

abx311417-20g 20 µg
EUR 162.5

Cyclin And CBS Domain Divalent Metal Cation Transport Mediator 1 (CNNM1) Antibody (Biotin)

abx311417-50g 50 µg
EUR 250

Cnnm4 (untagged) - Rat cyclin and CBS domain divalent metal cation transport mediator 4 (Cnnm4)

RN217195 10 µg Ask for price

Hiculture Transport Swab w/ Amies Medium

MQ651P-10NO 1 unit
EUR 7.97
Description: Hiculture Transport Swab w/ Amies Medium

Hiculture Transport Swab w/ Amies Medium

MQ651P-50NO 1 unit
EUR 29.96
Description: Hiculture Transport Swab w/ Amies Medium

HiCulture™ Transport Swabs w/Amies Mediu

MS684A-50NO 1 unit
EUR 46.87
Description: HiCulture™ Transport Swabs w/Amies Mediu

HiCulture™ Transport Swabs w/Amies Mediu

MS684B-50NO 1 unit
EUR 67.71
Description: HiCulture™ Transport Swabs w/Amies Mediu

HiCulture™ Transport Swabs w/Amies Mediu

MS684C-50NO 1 unit
EUR 88.58
Description: HiCulture™ Transport Swabs w/Amies Mediu

HiCulture™ Transport Swabs w/Amies Mediu

MS684D-50NO 1 unit
EUR 43.04
Description: HiCulture™ Transport Swabs w/Amies Mediu

Universal Transport Medium Coll Kit 3ml Naspharyn - PK50

305C PK50
EUR 392.85

Cnnm4 (myc-DDK-tagged) - Rat cyclin and CBS domain divalent metal cation transport mediator 4 (Cnnm4)

RR217195 10 µg Ask for price

Trueprep® AUTO Transport Medium for Swab Specimen Pack

60206TS05 5T
EUR 5

Trueprep® AUTO Transport Medium for Swab Specimen Pack

60206TS20 20T
EUR 20

Trueprep® AUTO Transport Medium for Swab Specimen Pack

60206TS50 50T
EUR 50

Transport Canister

M-CBP-PTC1 1 UNIT
EUR 500
Description: Transport Canister

HiCultureTM Transport Swabs w/ Amies Med

MS684S-50NO 1 unit
EUR 27.62
Description: HiCultureTM Transport Swabs w/ Amies Med

LSG Sample Collection Kit with Viral Transport Medium 1mL in 7mL with Swab in a Pouch - 1KIT

SWA3362 1KIT
EUR 7.09

LSG Sample Collection Kit with Viral Transport Medium 3mL in 7mL with Swab in a Pouch - 1KIT

SWA3366 1KIT
EUR 7.2

LSG Sample Collection Kit with Viral Transport Medium 2mL in 7mL with Swab in a Pouch - 1KIT

SWA3370 1KIT
EUR 7.15

Michel's Transport Fluid

MTF-10000 10 L
EUR 572.15

Michel's Transport Fluid

MTF-20000 20 L
EUR 1036.28

Michel's Transport Fluid

MTF500 500 ml
EUR 38.59

Michel's Transport Fluid

MTF999 1000 ml
EUR 61.72

LSG Sample Collection Kit with Viral Transport Medium 1mL in 12mL with Swab in a Pouch - 1KIT

SWA3360 1KIT
EUR 7.39

LSG Sample Collection Kit with Viral Transport Medium 3mL in 12mL with Swab in a Pouch - 1KIT

SWA3364 1KIT
EUR 7.48

LSG Sample Collection Kit with Viral Transport Medium 2mL in 12mL with Swab in a Pouch - 1KIT

SWA3368 1KIT
EUR 7.42

HiCulture™ Transport Swab w/Selenite Med

MS052A-50NO 1 unit
EUR 27.62
Description: HiCulture™ Transport Swab w/Selenite Med

Sample Transport Reagent

SSFIN-0007 20mL
EUR 32

PBS Transport Tube 1ml

PBS1000-100 each
EUR 60

PBS Transport Tube 1ml

PBS1000-400 each
EUR 216

Sterile Viral Transport and Preservation Medium; Flat Bottom Tube (100 x 1 ml vials)

BSV-VTM-003 100 x 1 ml
EUR 316
Description: Sterile Viral Transport and Preservation Medium; Flat Bottom Tube (100 x 1 ml vials)

Sterile Viral Transport and Preservation Medium; Flat Bottom Tube  (500 x 1 ml vials)

BSV-VTM-004 500 x 1 ml
EUR 1390
Description: Sterile Viral Transport and Preservation Medium; Flat Bottom Tube  (500 x 1 ml vials)

Sterile Viral Transport and Preservation Medium; Flat Bottom Tube  (100 x 3 ml vials)

BSV-VTM-005 100 x 3 ml
EUR 405
Description: Sterile Viral Transport and Preservation Medium; Flat Bottom Tube  (100 x 3 ml vials)

Sterile Viral Transport and Preservation Medium; Flat Bottom Tube  (500 x 3 ml vials)

BSV-VTM-006 500 x 3 ml
EUR 1896
Description: Sterile Viral Transport and Preservation Medium; Flat Bottom Tube  (500 x 3 ml vials)

UTM Transport Tubes - PK50

350C PK50
EUR 255.15

Sterile Viral Transport and Preservation Medium; Conical Bottom Tube (100 x 3 ml vials)

BSV-VTM-001 100 x 3 ml
EUR 405
Description: Sterile Viral Transport and Preservation Medium; Conical Bottom Tube (100 x 3 ml vials)

Sterile Viral Transport and Preservation Medium; Conical Bottom Tube  (500 x 3 ml vials)

BSV-VTM-002 500 x 3 ml
EUR 1896
Description: Sterile Viral Transport and Preservation Medium; Conical Bottom Tube  (500 x 3 ml vials)

Michel's Transport Wash Buffer

MTW-10000 10 L
EUR 527.13

Michel's Transport Wash Buffer

MTW-20000 20 L
EUR 1001.55

Michel's Transport Wash Buffer

MTW500 500 ml
EUR 38.59

Michel's Transport Wash Buffer

MTW999 1000 ml
EUR 61.72

Sterilin Transport Swabs - PK25

147C PK25
EUR 74.25

HiCultureTM Transport Swabs w/

MS1062-100NO 1 unit
EUR 46.04
Description: HiCultureTM Transport Swabs w/

HiCultureTM Transport Swabs w/

MS1062-10NO 1 unit
EUR 9.27
Description: HiCultureTM Transport Swabs w/

HiCultureTM Transport Swabs w/

MS1062-50NO 1 unit
EUR 27.62
Description: HiCultureTM Transport Swabs w/

HiCultureTM Transport Swabs w/

MS113-100NO 1 unit
EUR 46.04
Description: HiCultureTM Transport Swabs w/

HiCultureTM Transport Swabs w/

MS113-10NO 1 unit
EUR 9.27
Description: HiCultureTM Transport Swabs w/

HiCultureTM Transport Swabs w/

MS113-50NO 1 unit
EUR 27.62
Description: HiCultureTM Transport Swabs w/

boite de 200 filtres pour cytologie, 24 x 76 mm + 1 trou 7 mm

CY430F2476/1T 200
EUR 13.1

boite de 200 filtres pour cytologie, 26 x 63 mm + 1 trou

CY430F2663/1T 200
EUR 13.1

Protein Transport Inhibitor MIX

E-CK-A013-200Tests 200 Tests
EUR 85

Protein Transport Inhibitor MIX

E-CK-A013-500Tests 500 Tests
EUR 135

Protein Transport Inhibitor MIX

E-CK-A013-50Tests 50 Tests
EUR 30

Protein Transport Inhibitor MIX

E-CK-A013-each each Ask for price

boite de 200 filtres pour cytologie, 25 x 75 mm + 2 trous

CY430F2575/2T 200
EUR 13.1

Cytological Sampling Brush - PK100

CYT1050 PK100
EUR 63.45

Swab Transport Amies Wire - PK500

SWA3020 PK500
EUR 2177.55

Fixative, for fixing cytological or hist

S102-500ML 1 unit
EUR 31.73
Description: Fixative, for fixing cytological or hist

DuraPorter Transport Box Red - EACH

STO0002 EACH
EUR 206.55

Sterile 5mL Transport Tube (Axygen)

TUBE5AX-S2 500box
EUR 267.6
Description: Skirted screw-cap 5mL Axygen tubes with caps. Sterile, RNase & DNase free.

Golgi Transport 1A (GOLT1A) Antibody

20-abx215662
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

Golgi Transport 1A (GOLT1A) Antibody

20-abx325291
  • Ask for price
  • Ask for price
  • 100 ug
  • 50 ug

Swab Transport Amies Plastic - PK500

SWA3016 PK500
EUR 473.85

Golgi Transport 1A (GOLT1A) Antibody

abx325291-100g 100 µg
EUR 250

Golgi Transport 1A (GOLT1A) Antibody

abx325291-50g 50 µg
EUR 187.5

Nuclear Transport Factor 2 Protein

20-abx260609
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

HiCultureTM Transport Swabs w/ Cary -

MS202-100NO 1 unit
EUR 46.04
Description: HiCultureTM Transport Swabs w/ Cary -

HiCultureTM Transport Swabs w/ Cary -

MS202-10NO 1 unit
EUR 9.27
Description: HiCultureTM Transport Swabs w/ Cary -

HiCultureTM Transport Swabs w/ Cary -

MS202-50NO 1 unit
EUR 27.62
Description: HiCultureTM Transport Swabs w/ Cary -

HiCultureTM Transport Swabs w/ CVTR

MS316-100NO 1 unit
EUR 46.04
Description: HiCultureTM Transport Swabs w/ CVTR

HiCultureTM Transport Swabs w/ CVTR

MS316-10NO 1 unit
EUR 9.27
Description: HiCultureTM Transport Swabs w/ CVTR

HiCultureTM Transport Swabs w/ CVTR

MS316-50NO 1 unit
EUR 27.62
Description: HiCultureTM Transport Swabs w/ CVTR

Swab Transport Amies Charcoal - PK500

SWA3018 PK500
EUR 473.85

DuraPorter Transport Box Clear - EACH

STO0001 EACH
EUR 180.9

Transport Tubes 10ml SIMPORT - PK1000

T55210ATTP PK1000
EUR 197.1

Nuclear Transport Factor 2 Protein

abx260609-10g 10 µg
EUR 325

Nuclear Transport Factor 2 Protein

abx260609-2g 2 µg
EUR 225

HiCultureTM Transport Swabs w/ Amies

MS651-100NO 1 unit
EUR 46.04
Description: HiCultureTM Transport Swabs w/ Amies

HiCultureTM Transport Swabs w/ Amies

MS651-10NO 1 unit
EUR 9.27
Description: HiCultureTM Transport Swabs w/ Amies

HiCultureTM Transport Swabs w/ Amies

MS651-50NO 1 unit
EUR 27.62
Description: HiCultureTM Transport Swabs w/ Amies

HiCultureTM Transport Swabs w/ Amies

MS684-100NO 1 unit
EUR 46.04
Description: HiCultureTM Transport Swabs w/ Amies

HiCultureTM Transport Swabs w/ Amies

MS684-10NO 1 unit
EUR 9.27
Description: HiCultureTM Transport Swabs w/ Amies

Every gynecologic cytology specimen examined by each a CT and a CP from December 2004 to March 2015 was extracted from the laboratory info system; glandular interpretations have been excluded. Excel and SAS have been used for CT-CP pair evaluation. CT-CP pairs with fewer than 32 specimens (the bottom quartile) have been excluded. For the remaining CT-CP pairs, 30 specimens or 10% of the specimens (whichever was greater) have been randomly chosen for comparability by a weighted κ statistic. κ values larger than 0.6 represented good settlement inside CT-CP pairs.